Botanical Extracts | Manufacturer and supplier of natural ingredients.
One-stop integrated procurement of bioactive peptides, APIs and natural sweeteners. Streamline your procurement process with Blue Eyes Biotech.
WhatsApp supply Chain
660840769830
English
Grape Seed Extract 95% OPC (HPLC Verified)
QR code
share
Blue Eye Bio's 95% OPC Grape Seed Extract is HPLC-verified to isolate exclusively the low-molecular-weight oligomeric fraction (dimers to tetramers) — the only portion your customers' bodies actually absorb.
Unlike standard UV-Vis 95% extracts that include non-bioavailable polymeric tannins, our HPLC absolute quantification confirms every milligram on your label is biologically active.
Key specifications:
- Assay: ≥95% OPC by HPLC
- Solvent: Ethanol/Water — Zero Hexane
- Heavy Metals: Pb<1ppm, As<0.5ppm (ICP-MS)
- MOQ: 1 kg | Lead time: 7–14 days
- Each batch ships with individual HPLC chromatogram
Certifications: GMP · ISO 9001 · Halal · Kosher
Unlike standard UV-Vis 95% extracts that include non-bioavailable polymeric tannins, our HPLC absolute quantification confirms every milligram on your label is biologically active.
Key specifications:
- Assay: ≥95% OPC by HPLC
- Solvent: Ethanol/Water — Zero Hexane
- Heavy Metals: Pb<1ppm, As<0.5ppm (ICP-MS)
- MOQ: 1 kg | Lead time: 7–14 days
- Each batch ships with individual HPLC chromatogram
Certifications: GMP · ISO 9001 · Halal · Kosher
DetailＦＡＱ
Standardized 95% OPC (HPLC Verified): The Zenith of Bioavailable Antioxidants
In the world of polyphenols, molecular size determines efficacy. At Blue Eye Bio, we don't simply provide "95% Proanthocyanidins" — we provide Oligomeric Procyanidins (OPC): the low-molecular-weight fraction that your body can actually absorb.
Refined through precision ethanol-water extraction and verified by HPLC absolute quantification, our pharmaceutical-grade extract is built for high-stakes formulations where cellular absorption and clinical results are non-negotiable. Every batch ships with an individual HPLC chromatogram — not a generic certificate.
Refined through precision ethanol-water extraction and verified by HPLC absolute quantification, our pharmaceutical-grade extract is built for high-stakes formulations where cellular absorption and clinical results are non-negotiable. Every batch ships with an individual HPLC chromatogram — not a generic certificate.
95% OPC Grape Seed Extract HPLC Verified by Blue Eye Bio
We don't deliver "95% polyphenols" — we deliver exclusively low-molecular-weight Oligomeric Procyanidins, confirmed by HPLC chromatography for absolute purity and maximum cellular bioavailability.
1. Technical Matrix
| Analysis Item | ||
Technical · Specifications
Product Specification Matrix
Structured data for R&D review, regulatory dossiers, and procurement approval. Designed to be screen-readable and Google-crawlable via Product schema markup.
| Analysis Item | Specification | Testing Method |
|---|---|---|
| Active Component | Oligomeric Procyanidins (OPC) | HPLC — Absolute |
| Assay (Purity) | ≥ 95.0% | HPLC Verified |
| Molecular Profile | Low MW — Dimers to Tetramers | GPC / HPLC |
| Appearance | Fine Reddish-Brown Powder | Visual |
| Particle Size | 100% through 80 mesh | Sieve Analysis |
| Moisture | ≤ 5.0% | Karl Fischer |
| Solvent Residue | Zero Hexane — Ethanol/Water Only | GC-FID |
| Heavy Metals | Pb < 1 ppm · As < 0.5 ppm | ICP-MS (USP/EP) |
| Microbiology | TPC < 1000 CFU/g · Salmonella Neg | USP <61> |
| Shelf Life | 24 months (sealed, cool, dry) | Stability Study |
| Certifications | GMP · ISO 9001 · Halal · Kosher | Audit Verified |
Technical Education · H2
Solving the "Purity Mirage":
HPLC vs. UV-Vis — What Your Supplier Isn't Telling You
Many suppliers advertise 95% purity using UV-Vis spectrophotometry — a method that measures total light absorption, not molecular identity. The result: a number that includes large, non-absorbable polymeric tannins that your customers' bodies excrete unused. At Blue Eye Bio, our 95% is an HPLC absolute figure — meaning 95% of what's in the bottle is biologically active OPC.
Key takeaway for your label: When you source 95% OPC (HPLC) from Blue Eye Bio, every milligram on your Supplement Facts panel is verifiably active. That's the promise you can make to your end customer — and defend in any regulatory review.
Product Asset · HPLC Chromatogram
Chromatographic Comparison: Blue Eye Bio 95% OPC (HPLC) vs. Industry Standard 95% PAC (UV)
illustrates the molecular difference between HPLC and UV-Vis graded extracts.
Industry Standard 95% Proanthocyanidins (UV-Vis Grade)
Same nominal purity claim — very different molecular reality.
Alt text: "HPLC chromatogram comparison showing clean low-molecular-weight OPC peaks in Blue Eye Bio grade versus large polymeric tannin hump in standard UV-grade extract."
Market · Applications
Industrial R&D Applications
Blue Eye Bio's 95% OPC (HPLC) is specified across four premium market segments where bioavailability and documentation standards are non-negotiable.
Premium Longevity Supplements
Ideal as a core antioxidant anchor in NAD⁺ synergistic stacks, cellular repair formulas, and next-generation anti-aging protocols. HPLC documentation satisfies retailer compliance requirements at Whole Foods, iHerb, and Amazon Premium.
Cardiovascular Therapeutics
Used in clinically-referenced formulations targeting vascular elasticity, endothelial function, and micro-circulation optimization. OPC dimers are the key active for nitric oxide pathway support.
High-End Cosmeceuticals
A potent topical and ingestible active for stabilizing collagen cross-links, inhibiting MMP enzymes, and preventing photo-oxidative skin aging from within. 100% water-soluble — compatible with serum and beauty shot formats.
Pharmaceutical R&D
Low-molecular-weight OPC fractions are referenced in peer-reviewed research on neuroinflammation, metabolic syndrome, and ocular health. Our HPLC chromatograms are accepted for IND-enabling study submissions.
Process · Quality Assurance
From Vineyard to Chromatogram:
Our 5-Stage Quality Protocol
01
Raw Material Selection — Vitis vinifera Seed
Sourced exclusively from Vitis vinifera seeds with documented varietal provenance. Incoming material is screened for pesticide residues (EU MRL compliance) and initial polyphenol density before any processing begins.
02
Solvent-Controlled Ethanol/Water Extraction
Zero hexane. Our proprietary extraction uses pharmaceutical-grade ethanol and purified water, preserving the integrity of the low-molecular-weight OPC fraction while eliminating the solvent residues common in commodity-grade material.
03
Molecular Weight Fractionation
Precision chromatographic fractionation isolates the dimer-to-tetramer fraction and removes high-molecular-weight polymeric tannins. This is the step that most suppliers skip — and the reason our HPLC value is a real 95%, not a UV artifact.
04
HPLC + GPC Dual Verification
Every production batch undergoes dual analytical verification: HPLC for absolute OPC content and GPC for molecular weight distribution. A unique batch-specific chromatogram is generated and attached to each Certificate of Analysis.
05
ICP-MS Heavy Metal Screening + Release QC
Final release testing includes ICP-MS for Pb, As, Cd, Hg (USP/EP limits), full microbiological panel, and moisture verification. Batch is held until all parameters are confirmed. Release documentation package available for EU/US market entry.
Business · SME Enablement
Technical & Commercial Support
for Emerging Brands
Blue Eye Bio was built for brands that compete on ingredient quality, not commodity price. Here is the infrastructure we provide to small and medium-sized supplement, cosmetic, and pharmaceutical businesses.
Documentation
Full Technical Dossier
Every batch includes: HPLC chromatogram, GPC molecular weight profile, ICP-MS heavy metals report, microbiological CoA, and a shelf-life stability summary. Formatted for EU Annex III and US dietary supplement facility filings.
Most Requested
Request a Verified Sample
Evaluate 1–5 kg of our 95% OPC (HPLC) in your formulation before committing to bulk. Sample shipments include full analytical documentation. We do not ship un-tested, un-documented samples.
Procurement
Bulk Wholesale Pricing
Scale from 1 kg (R&D validation) to 500 kg (commercial launch) with no re-qualification required. FOB Shenzhen and CIF pricing available. Lead time: 7–14 business days from order confirmation.
Blue Eye Bio GMP Certified Manufacturer
Looking for a more cost-effective option for bulk food and beverage applications?
→ View our Standard 95% Proanthocyanidins (UV) grade — optimized for high-volume food & supplement manufacturingFAQ · Long-Tail SEO
Frequently Asked Questions
Our HPLC method distinguishes genuine grape seed OPC from pine bark and peanut skin adulterants by retntion time and peak ratio — substances that pass UV-Vis testing are identifiable by HPLC chromatography. Every batch includes a signed Statement of Composition, and DNA botanical authentication reports are available on request for clients requiring full chain-of-custody documentation.
Why should I specify 95% OPC (HPLC) over standard grape seed extract?
Standard 95% extracts are assayed by UV-Vis, which counts non-absorbable polymeric tannins. Blue Eye Bio's HPLC grade isolates exclusively the bioactive oligomeric fraction. What's on your label is what your customers actually absorb.
What is the difference between OPC and Proanthocyanidins (PAC)?
PAC is the broad class including all polymerization degrees. OPC refers specifically to the low-MW fraction — dimers, trimers, tetramers — that crosses the intestinal barrier and is biologically active. Our HPLC method measures OPC specifically.
Is your grape seed extract 100% water soluble?
Yes. Our 95% OPC (HPLC) disperses completely in water at room temperature, producing a clear reddish-amber solution with no particulate. Compatible with functional beverages, liquid beauty shots, and water-based topical formulations.
What documentation is available for EU / US regulatory submissions?
Each batch includes: HPLC chromatogram, GPC molecular weight report, ICP-MS heavy metals (USP/EP), full microbiological CoA, GC-FID residual solvent report, and a signed Statement of Composition. Covers EU Article 17, US dietary supplement, and Australian TGA requirements.
What is the minimum order quantity and lead time?
MOQ is 1 kg for R&D samples; commercial orders from 5 kg. Lead time: 1days.
How do you verify there is no pine bark or peanut skin adulteration?
Our HPLC method detects adulterants by retention time and peak ratio — substances that pass UV-Vis testing are identifiable by HPLC. Every batch includes a signed Statement of Composition, and DNA botanical authentication reports are available on request.
Compliance & Support
GMP, ISO, HALAL, KOSHER, FDA Registered.
Full technical dossiers (MSDS, TDS, COA, Allergen Statement) are available for every batch.
Address：7 COPPERFIELD ROAD, COVENTRY, WEST MIDLAND, ENGLAND UNITED KINGDOM, CV2 4AQ
WhatsApp(supply chain)：66-0840769830
Contact email:：[email protected]
Committed to the research and development, production and sales of natural plant extracts, focusing on high-purity ingredients and following EU and US certification standards.
Organic ingredients products
Plant essential oils
Blue Eye Biotechnology is a professional manufacturer and supplier with a history of 20 years, focusing on high-purity specialty raw materials. We provide precise solutions for anti-aging, Oncology Research and Immune Support, and natural sweetness through a factory-direct supply chain.
contact us