Heparin sodium
Heparin Sodium API: High-Potency Bio-Ingredients with End-to-End Traceability
Sourced through the Blue Eyes Bio Integrated Resource System & GMP-Certified Partners.
Product Info of Heparin Sodium ：Heparin Sodium: Potent, Systemic, Anticoagulant
What is Heparin Sodium?
Heparin sodium is a natural anticoagulant drug belonging to the glycosaminoglycan family. It is primarily extracted from porcine small intestine or bovine lung. Clinically, it is the world's most important and essential anticoagulant, used to prevent and treat thromboembolic diseases.
Essence: Sodium heparin is the sodium salt of a sulfated mucopolysaccharide extracted from the small intestinal mucosa of pigs or cattle. It belongs to the glycosaminoglycan (GAGs) family and has a structure similar to familiar substances like hyaluronic acid and chondroitin sulfate.
Physical Properties: White or off-white powder with extremely strong hygroscopicity and water solubility.
Production Process Overview: Pig small intestine procurement -> Mucosal separation -> Enzymatic hydrolysis/resin adsorption -> Crude heparin -> Refining and purification -> Precipitation and drying -> Finished heparin sodium.
Core Functions and Efficacy
Main Functions: Extremely strong anticoagulant and antithrombotic effects
Clinical Applications: Primarily administered by injection for surgery, cardiovascular emergencies, and hemodialysis.
Cosmetic Applications: Focused on potent anti-inflammatory effects and adjunctive treatment of severe congestion (due to its extremely high potency, the dosage must be strictly controlled).
Medical Efficacy (Pharmaceutical Perspective)
Anticoagulant and Antithrombotic: Interferes with multiple stages of the coagulation process.
Lowering Blood Lipids: Promotes the release of lipoprotein lipase from vascular endothelium, accelerating blood lipid clarification.
The "Killer Feature" of Sodium Heparin in Cosmetics
Compared to heparin-like substances, sodium heparin has three irreplaceable functions in skincare products:
Rapidly Reduces Swelling/Redness: Sodium heparin rapidly reduces subcutaneous bruising and redness after cosmetic procedures (such as mesotherapy and microneedling).
Improves "Vascular" Dark Circles: Acts directly on capillaries, improving blood flow.
Synergizes Peptide Absorption: It can alter the permeability of the skin's extracellular matrix, allowing fish collagen peptides or hydrolyzed casein peptides to more easily reach the dermis.
Product Name: Heparin Sodium
CAS: 9041-08-1
Purity: ≥150 IU (available in 160 IU, 170 IU, and 180 IU)
Packaging Information: Available as per customer specifications
Appearance: White to off-white amorphous powder.
Solubility: Freely soluble in water, insoluble in organic solvents such as ethanol and acetone.
Impurity Control:
Protein: Not detectable
Heavy Metals: ≤ 10 ppm
Total Ash: ≤ 1.0%
Technical Specifications
| Specification | Pharmaceutical Grade (API) | Cosmeceutical Grade |
| Standard | USP / EP / ChP | Internal In-house Standard |
| Potency | ≥ 150 IU/mg (Customizable) | Optimized for Transdermal |
| Origin | Porcine Intestinal Mucosa | Porcine Intestinal Mucosa |
| Certifications | GMP, ISO 9001, CEP (Ready) | ISO, COA, MSDS |
| Appearance | White to off-white powder | White fine powder |
Our raw materials are sourced exclusively from healthy porcine mucosa, following strict viral inactivation protocols."
Why Choose Us?-BLUE EYES BIO
GMP-Certified Manufacturing: All production is carried out in state-of-the-art facilities that strictly adhere to GMP (Good Manufacturing Practice). We ensure product purity and biological activity from the source.
Systematic Management (Integrated System): Through the Blue Eyes Bio resource system, we manage the entire lifecycle—from crude heparin collection to refined API production. This reduces price volatility and ensures 100% traceability.
Quality Assurance & Compliance: We provide comprehensive documentation, including COA, Method of Analysis (MOA), and Stability Data, simplifying your regulatory approval process.
Strategic Collaboration: Our partnership with top-tier pharmaceutical plants allows us to offer high-volume supply and customized potency levels to meet specific formulation needs.
"Bridging the Gap Between Quality and Compliance."
Looking for a reliable Heparin Sodium partner with a robust GMP-backed supply chain? Blue Eyes Bio provides the systematic management required for high-stakes pharmaceutical applications.
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Q1: Is Blue Eyes Bio’s Heparin Sodium manufactured in a GMP-certified facility?
A: Yes. All Heparin Sodium supplied by Blue Eyes Bio is produced in state-of-the-art facilities that strictly adhere to GMP (Good Manufacturing Practice) standards. Through our integrated resource system, we partner exclusively with top-tier pharmaceutical plants to ensure that every batch meets international safety and quality benchmarks.
Q2: Which pharmacopeia standards does your Heparin Sodium comply with?
A: Our Heparin Sodium API is manufactured to meet and exceed the requirements of the USP (United States Pharmacopeia), EP (European Pharmacopoeia), and ChP (Chinese Pharmacopoeia). We provide a comprehensive Certificate of Analysis (COA) with every shipment to verify compliance with these global standards.
Q3: How does the Blue Eyes Bio "Integrated Resource System" benefit my supply chain?
A: Our system integrates the entire supply chain, from the collection of porcine intestinal mucosa to the final API refining. For our Western partners, this means:
Total Traceability: Full documentation from raw material origin to the finished product.
Price Stability: Mitigation of market fluctuations through strategic resource management.
Consistent Potency: Specialized control over biological activity levels (IU/mg) tailored to your specific formulation needs.
Q4: What is the biological source and safety protocol for your Heparin?
A: Our Heparin Sodium is derived exclusively from healthy porcine (pig) intestinal mucosa. Within the Blue Eyes Bio quality management framework, we employ rigorous viral inactivation protocols and multi-stage purification processes to ensure the highest level of biological safety and purity.
Q5: Can I use your Heparin Sodium in high-end cosmeceutical formulations?
A: Absolutely. While we provide Pharmaceutical Grade API, we also offer a specialized grade for Cosmeceuticals. Heparin Sodium is highly effective in skincare for improving microcirculation, reducing the appearance of dark circles, and soothing inflammatory skin conditions. Our technical team can assist in optimizing its stability within your topical formulations.
Q6: What documentation can Blue Eyes Bio provide for regulatory filing?
A: We support our clients with a full regulatory data package, including:
GMP Certificates
COA (Certificate of Analysis)
MSDS (Material Safety Data Sheet)
Stability Testing Data
Method of Analysis (MOA)
Compliance & Support
