Combat Skin Glycation: Rosaceae Berry Polyphenol-Polysaccharide ComplexReduces AGEs Deposition by 62% In Vivo

2025-07-14 12:07

Article Title  

Combat Skin Glycation: Rosaceae Berry Polyphenol-Polysaccharide ComplexReduces AGEs Deposition by 62% In Vivo  

Details PageDescription  

Glycation-induced AGEs (Advanced Glycation End Products)stiffen skin collagen, driving wrinkles and loss of elasticity This in vivostudy demonstrates how a proprietary polyphenol-polysaccharide complex from Rosaceaeberries (strawberry, raspberry, blackberry) significantly reverses AGEsaccumulation in animal models:  


Key Findings  

▶️ 62% Reduction in Skin AGEs  

After 8-week supplementation (50mg/kg/day), quantified via fluorescent AGEs-specific imaging (p<0001)  

▶️ Dual-Action Mechanism:  

- Polyphenols (ellagitannins, anthocyanins)scavenge carbonyls → block new AGEs formation,  

- Berry polysaccharides ↑ macrophage clearance of existingAGEs by 31-fold  

▶️ Visible Rejuvenation:  

+38% skin elasticity & +29% hydrationvs control group (correlated with collagen I preservation)  


Formulation Insights:  

•TopicalSerums: Low-MW complex penetrates stratum corneum, inhibiting glycation atsource  

•Oral BeautySupplements: Systemic reduction of AGEs validated by blood/skin biomarkers  

•SynergyBoost: Combines with carnosine for 2x greater efficacy than single actives  


Blue Eyes Biotech CO, Ltd pioneers clinically-validatedRosaceae berry extracts:  

✅ Dual-Extraction Technology: Preservesheat-sensitive polyphenols & bioactive polysaccharides  

✅ Standardized Complex: 40% polyphenols +30% polysaccharides (HPLC/UV verified)  

✅ Clean & Sustainable: Wild-harvestedberries, ECOCERT® compliant  


Procurement Advantages:  

→In vivo dose-responsedata: Enables precise dosing for cosmetics/nutraceuticals  

→Water-soluble& oil-dispersible formats: Seamless integration into any formulation  

→Full dossiersupport: Anti-glycation efficacy data, stability tests, safety profiles (OECDcompliant)  


Lead the Anti-Glycation Revolution:  

Download whitepaper or request AGEsinhibition assay reports:  

[email protected] | www.blueeyes-bio.com


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