NHDC (Neohesperidin Dihydrochalcone) – The Ultimate Bitterness Blocker & Intense Sweetener (CAS20702-77-6)

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High Purity: ≥ 98% (HPLC), strictly following USP/EP/FCC standards.

High Stability: Heat-stable and acid-stable—perfect for pasteurized beverages and extruded feed.

High Potency: Effectively masks the bitter aftertaste of plant proteins, vitamins, and APIs at low dosage (ppm).

High Traceability: Direct supply from our Asian core factory with unified international quality management.

High Flexibility: 12-hour response, flexible MOQ, and R&D samples dispatched
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NHDC (Neohesperidin Dihydrochalcone) Manufacturer | 1500x Intense Sweetness | Blue Eyes Biotech

Product Details


1.Specifications


ItemSpecifications (EP/USP Standard)
Product NameNeohesperidin Dihydrochalcone (NHDC)
SourceNatural Citrus Aurantium L.
Purity (HPLC)≥98.0%
CAS No.20702-77-6
Melting Point156℃ - 159℃
SolubilitySoluble in water & ethanol
Caloric Value0 kcal/g
CertificationsISO9001, Halal, Kosher, FSSC22000


Technical Specifications

Analysis ItemSpecification (USP/EP/FCC)Test Method
AppearanceWhite to Off-white Crystalline PowderVisual
Assay (NHDC)≥ 98.0%HPLC
CAS Number20702-77-6/
Molecular FormulaC28H36O15/
Loss on Drying≤12.0%105℃ , 3h
Heavy Metals≤ 10 ppmICP-MS
Lead (Pb)≤ 1 ppmICP-MS
Total Plate Count≤ 1000 cfu/gUSP




Why choose NHDC from BLUE EYES BIOTECH?

We are more than just a conduit; we are an extension of your raw material strategy. Blue Eyes Biotech utilizes our own core facility in Asia to rigorously control every step from citrus extract to hydrogenation synthesis.


Our NHDC not only provides exceptional sweetness but also focuses on addressing bitter residue issues in food, pharmaceuticals, and animal feed. With 20 years of industry experience, we offer customized sugar reduction solutions to global clients that meet the highest international standards (USP/EP).


Flexible MOQ: Emphasizing support for purchases ranging from 1kg to tons, meeting the needs of small and medium-sized formulation plants.


offer one-stop procurement of over 2000 raw materials, including rare and hard-to-find ingredients. This saves you procurement costs and time, eliminating the need to deal with multiple suppliers and providing a worry-free and effortless service.


Fast Shipping via HK/Bangkok Hub: Emphasizing the use of logistics hubs in Hong Kong and Bangkok, and a stable and professional freight forwarding department with competitive pricing, offering more flexible customs clearance and faster international air freight response than mainland factories.


Free Testing Sample: "Request your 10g sample for R&D testing today!"



Selling Points


  1. Ultimate Bitterness Masking: Even at low concentrations, NHDC effectively suppresses bitterness from plant extracts, minerals, or pharmaceutical ingredients.

  2. Sweetness Synergy: When used in combination with stevia or monk fruit, it significantly enhances sweetness and eliminates metallic aftertaste.

  3. Excellent Stability: Remains stable during autoclaving or long-term storage, making it ideal for functional beverages and animal premixes.



Application Guide

  • Food: Sugar reduction in beverages, candies, and dairy.

  • Feed: Enhancing palatability in piglet and pet food.

  • Pharma: Masking the bitter taste of oral suspensions.





Comprehensive NHDC Solutions by Blue Eyes Biotech:As a leading NHDC manufacturer, we specialize in providing bulk Neohesperidin Dihydrochalcone for diverse industrial applications. Whether you need a natural bitterness blocker for pharmaceutical syrups or a high-intensity sweetener for calorie-reduced beverages, our NHDC (CAS 20702-77-6) delivers consistent performance. Our feed-grade NHDC is also widely used in animal nutrition to improve palatability. Blue Eyes Biotech ensures a reliable supply chain with standardized quality control directly from our Asia-based production alliance.


Industry-Specific Tags:
Neohesperidin Dihydrochalcone (NHDC), Intense Sweetener, Natural Bitterness Suppressor, CAS 20702-77-6, Flavor Enhancer for Animal Feed, Sugar Reduction Solutions, Pharmaceutical Excipients, Bitterness Masking Agent, Flavors & Fragrances Raw Materials, Non-caloric Sweetener, Blue Eyes Biotech Manufacturing, Citrus Aurantium Extract, Synergistic Sweetening Agents, Bulk Food Ingredients.

Q: What is the sweetness intensity of your NHDC?A: Our NHDC is approximately 1500 to 1800 times sweeter than sucrose at threshold concentrations.


Q: Is your NHDC stable under high temperatures?A: Yes, NHDC from Blue Eyes Biotech is highly stable under heat and acidic conditions, making it ideal for pasteurized beverages and extruded animal feed.


Q: Can I request a customized COA?

A: Certainly. As we manage our own core factory, we can provide batch-specific COAs and third-party testing reports to meet your regulatory requirements.


Compliance & Support

GMP, ISO, HALAL, KOSHER, FDA Registered.

Full technical dossiers (MSDS, TDS, COA, Allergen Statement) are available for every batch.