Sildenafil Mesylate (Salt Form API) CAS 139755-91-2

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Unlike the common citrate salt, Sildenafil Mesylate is preferred by formulation scientists for its enhanced aqueous solubility and unique dissolution profile, making it a critical component for Salt-form Screening and the development of novel delivery systems.
Key Technical Moats:
Assay: Minimum 99.0% verified by High-Performance Liquid Chromatography (HPLC).
Traceability: Governed by our Unified QC Standard (UQS) for absolute molecular integrity.
Documentation: We provide comprehensive technical dossiers (COA, MSDS, and TDS) to support your regulatory filings.
We offer Scalable Supply solutions for laboratories and large-scale pharmaceutical manufacturers, ensuring rapid market entry with first-hand manufacturer pricing.
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Sildenafil Mesylate (Methanesulfonate Salt Form API)


1.Product Introduction

Blue Eye Bio
provides Sildenafil Mesylate (CAS 139755-91-2) as a high-purity Active Pharmaceutical Ingredient (API) for global research and development. This methanesulfonate salt form is specifically refined for pharmaceutical scientists requiring an alternative to the standard citrate salt for specialized formulation studies.





2.Technical Specifications


Analysis Item

Specification

Testing Method

Chemical Name

Sildenafil Mesylate / Sildenafil Methanesulfonate

/

CAS Number

139755-91-2

/

Purity (HPLC)

≥ 99.0%

HPLC Verified

Solubility

Enhanced Aqueous Solubility (vs. Citrate)

Lab Test

Appearance

White to off-white crystalline powder

Visual



3.What is Sildenafil Mesylate and Why is it Used?



"While Sildenafil Citrate is the industrial standard, Sildenafil Mesylate offers distinct advantages in the Drug Development Pipeline. As a methanesulfonate salt, it exhibits a different dissolution profile and molecular stability."

    • Enhanced Solubility: Mesylate salts are often chosen by formulation researchers to improve the aqueous solubility of the API, allowing for potentially higher bio-availability in specific delivery systems.

    • Alternative Salt-Form Screening: Critical for laboratories performing Salt-form Optimization to circumvent patent hurdles or improve the shelf-life of the final dosage form.



4.Industrial R&D Applications


    • Novel Delivery Systems: Researching liquid formulations, fast-dissolving tablets, or transdermal patches.

    • Comparative Bio-equivalence Studies: Used as a reference compound in pre-clinical trials.

    • Chemical Synthesis: Serving as a pure substrate for derivative research in oncological or metabolic signaling.




5.The Blue Eye "First-hand" Edge

    • Unified QC Standard (UQS): Regardless of which alliance plant the raw materials come from, all methanesulfonates are 100% audited by our in-house HPLC laboratory.

    • First-hand Technical Support: Direct access to COA, MSDS, and Stability data through our UK technical hub.

    • Scalable Supply: We support Pharmaceutical SMEs and large-scale manufacturers with flexible MOQ and reliable global fulfillment.



Seeking the standard salt? View our [Sildenafil Citrate] series.


“Research-grade only. Not for direct human consumption.”


    • Q: How does Sildenafil Mesylate differ from Sildenafil Citrate?

        • A: The primary difference lies in the acid radical. Mesylate (methanesulfonic acid) often provides different crystal lattice energy compared to Citrate, which can lead to variations in solubility and hygroscopicity, crucial for specialized pharmaceutical formulations.

    • Q: Is your Sildenafil Mesylate compliant with international pharma standards?

        • A: Yes. Our Sildenafil Mesylate is refined to meet rigorous purity benchmarks equivalent to USP/EP guidelines. We provide full analytical characterization for every batch.


Compliance & Support

GMP, ISO, HALAL, KOSHER, FDA Registered.

Full technical dossiers (MSDS, TDS, COA, Allergen Statement) are available for every batch.