4-Amino-1-methyl-3-propyl-1H-pyrazole-5-carboxamide (CAS 139756-01-7)

CAS 139756-01-7
acts as the foundational molecular scaffold for the sildenafil synthesis pathway. Known as Pharma Intermediate 1, this pyrazole derivative provides the essential heterocyclic core required for building potent vasodilatory research compounds. At Blue Eye Bio, we ensure that this building block is refined to ≥99% HPLC purity, providing global manufacturers with the precision and batch-consistency needed for high-stakes pharmaceutical assembly.

"At Blue Eye Bio, we specialize in the high-purity isolation of critical pyrazole derivatives. CAS 139756-01-7 is a pivotal pharmaceutical intermediate used as the primary building block for the construction of the pyrazole ring system in various vasodilatory signaling research compounds.

Governed by our British technical standards and produced through our Asia-based manufacturing hub, we ensure this crystalline intermediate meets the rigorous analytical benchmarks required for large-scale API synthesis and advanced molecular assembly."

1.Technical Specification Sheet

"Chemically, CAS 139756-01-7 is a high-purity crystalline intermediate featuring a functionalized pyrazole ring. In the synthesis pathway of PDE5 inhibitors, this compound acts as the pivotal synthetic precursor.

Its specific arrangement of amino and carboxamide groups allows for efficient cyclization and coupling reactions. By utilizing Blue Eye Bio’s high-purity grade, manufacturers can significantly reduce the risk of 'impurity carryover' in subsequent synthesis steps (such as chlorosulfonation), ensuring a cleaner final yield and more stable crystallization in the finished active ingredient."

2.Technical Role & Application)

• Pyrazole Ring Assembly: Acts as the essential core for heterocycle-based medicinal chemistry.

• Active Component Precursor: A key synthetic precursor in the manufacturing pathway of PDE5 inhibitors.

• R&D Building Block: Utilized by research institutions for the synthesis of novel analogs targeting cGMP signaling pathways.

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• Molecular Traceability: Every batch is governed by our Unified QC Standard (UQS), including 1H-NMR and HPLC verification to ensure zero related substance carryover.

• Primary Sourcing Efficiency: Through our Strategic Supply Chain Alliance, we provide manufacturer-direct pricing, bypassing trading premiums.

• Rapid Documentation: Batch-specific COA, MSDS, and TDS provided within 24 hours to accelerate your regulatory audit process.

Looking for the next step in synthesis? View our [Sildenafil Chlorinated Derivative]